Research Journal of Chemistry

and Environment


Indexed in SCOPUS, Chemical Abstracts, UGC, NAAS, Indian Citation Index etc.



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Review Paper:

Effects of arsenic-induced toxicosis (Arsenicosis) on human health and its prevention

Mairaj Samya, Nagar Richa Dave, Rehman F. and Jindal Tanu

Res. J. Chem. Environ; Vol. 27(3); 116-123; doi: https://doi.org/10.25303/2703rjce1160123; (2023)

Abstract
Owing to widespread groundwater pollution, arsenic is one of the most extreme worldwide ecological toxicants and induces cytotoxic activity and other chronic diseases for millions of people and also animals. Because of geologic and anthropogenic activities, arsenic pollution is widely spread. Long-term toxicity caused by arsenic can lead to the development of arsenicosis related to skin lesions, hepatomegaly, splenomegaly, cognitive dysfunction, cardiovascular and peripheral vascular disease, hypertension, diabetes mellitus, hepatic fibrosis and hematological, gastrointestinal, immunological, endocrine and multicancer neurological disorders.

Till date no effective treatment or medicine is available in global market to prevent arsenic induced toxicosis. Only use of safe water and well nourished foods can help to prevent further exposure. Recently, chelation therapy is recognized as a good remedial action to reduce and to eliminate the acute arsenic toxicity.