Efficient biological
activity of acridine synthesised by using efficient nano catalyst
Sujatha G., Mathunika Devi A., Lesy Josephine J., Punitha P. and Ramanathan P.
Res. J. Chem. Environ.; Vol. 28(3); 56-60;
doi: https://doi.org/10.25303/283rjce056060; (2024)
Abstract
A simple and efficient protocol for 9-(4-methoxyphenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexa
hydroacridine-1,8(2H,5H)-dione (MPTH) was synthesised by conventional method by
using efficient nano catalyst. The crystallite sizes (L) and surface area (S) of
TiO2 are 10.44 nm and 140.32 m2/g. MPTH displayed wide inhibitions on the KB cell
appearance with IC50 values 25.06 μg. The IC50 values of the MPTH imply that methoxy
substituted compound holds more inhibitory effect against the cancer cells.
