The effectiveness
of Grewia hirsuta (Vahl.) as a nootropic on scopolamine-induced cognitive deficit
in young and aged mice
Chikkamath Vinuth, Kulkarni H. Venkatrao, Habbu V. Prasanna and Naik Nagappa Anantha
Res. J. Chem. Environ.; Vol. 28(5); 30-40;
doi: https://doi.org/10.25303/285rjce030040; (2024)
Abstract
The dementia and loss of cognitive nature among humans are becoming epidemics and
causing a socio-economic burden. Amnesia and cognitive behaviours are natural phenomena
due to aging. The studies in young and aged mice were conducted in order to rule
out the impact of aging. It has become necessary to find novel nootropic agents
that are derived from natural resources. In synthetic drugs, we have a piracetam
prototype nootropic. The natural products obtained from plant sources are safe and
compatible with physiological conditions. Hence, we hope our scientific research
may lead to novel nootropic agents with fewer side effects. Nootropic activity was
assessed by elevated plus maze and T-maze activity of plant-based extracts with
standard piracetam.
