Synthesis, Characterization
and in vitro evaluation of Magnesium oxide Nanoparticles as Potential Anti-diabetic
agents
Gnaneswari Kongara, Kokkanti Sabeeha Tabassum, Yogini Sai Kalyani C., Chandana Sree
K. and Kumari Chitturi Ch M.
Res. J. Biotech.; Vol. 20(4); 168-176;
doi: https://doi.org/10.25303/204rjbt1680176; (2025)
Abstract
The current study objective is to synthesize Mgo nanoparticles through green mediated
means employing leaf extracts from Acalypha indica for biological purposes. The
produced Mgo nanoparticles' optical, chemical and morphological characteristics
were verified using UV–Vis spectroscopy, FT-IR, zeta potential, XRD and FE-SEM,
in that order. Mgo nanoparticles' optical properties and functional groups were
examined using UV visible absorption spectra and FT-IR analysis. The antibacterial
evaluation of the generated Mgo nanoparticles was investigated using the disc diffusion
method against microbial pathogens, including Gram-positive bacteria Staphylococcus
aureus and Bacillus subtilis, as well as Gram-negative bacteria Escherichia coli
and Klebsiella pneumoniae.
Amazing in vitro antibacterial, antioxidant and anti-diabetic properties of Mgo
Nanoparticles synthesised using green assisted synthesis were noted. As a result,
the current study concludes that environmentally safe, low-cost and green mediated
magnesium oxide nanoparticles are the best materials for biological applications.
