Review Paper:
Dynamics of Bacterial
and Fungal Degradation of Ibuprofen, a Potential Environmental Contaminant
Jayadevan Pavithra, Chacko Rita Rose, Sankarakumar Leelavathy Bhama and Sarojini
Suma
Res. J. Biotech.; Vol. 20(8); 308-317;
doi: https://doi.org/10.25303/208rjbt3080317; (2025)
Abstract
Ibuprofen is a nonsteroidal anti-inflammatory medication with analgesic and antipyretic
properties used in the pharmaceutical sector. The rising usage of this medicine
has hurt the environment, particularly aquatic life. This necessitates the use of
various procedures for degrading this chemical. As aggressive chemical treatment
procedures, particularly advanced oxidation processes (AOP) are marked by severe
reaction conditions. Bioremediation technologies based on microbial strains appear
to be a potential alternative.
Bacterial biodegradation, the most common kind of biodegradation, often happens
via side chain hydroxylation, whereas, various fungal extracellular enzymes rely
on oxidation of ibuprofen and subsequent breakdown into less toxic metabolites.
This review provides an extensive overview of different microbial degradation techniques
for a sustainable way of Ibuprofen degradation.
