Review Paper:
A Comprehensive
Overview of Bacterial Antibiotic Resistance: Insights, Methods and Future Prospects
Singh Priyambada and Arsi Laiba
Res. J. Biotech.; Vol. 20(6); 208-214;
doi: https://doi.org/10.25303/206rjbt2080214; (2025)
Abstract
Antimicrobial-resistant bacteria have emerged as a significant contributor to global
mortality and morbidity. Upon the initial introduction of antibiotics in the 1900s,
it was believed that mankind had triumphed over germs. It was then revealed that
the bacteria might acquire resistance to any administered medications. Many pathogenic
bacteria possess the ability to develop resistance to specific antimicrobial drugs.
The primary causes of resistance include restricting drug uptake, altering drug
targets, inactivating drugs and actively expelling drugs. These processes are inherent
to the bacteria or are obtained from other microbes. Gaining further insight into
these pathways would result in improved treatment alternatives for infectious disorders
and the creation of antimicrobial medicines capable of resisting microbial resistance.
