Exploring the
Phytochemical, Antioxidant, Antimicrobial and Anticancer Potential of Callistemon
citrinus (Red Bottlebrush) Bark Extracts in Bone Cancer Cell Line
Sindhu B., Perumal Elumalai, Sridevi Muruhan and Senthil Nathan M.
Res. J. Biotech.; Vol. 20(6); 66-75;
doi: https://doi.org/10.25303/206rjbt066075; (2025)
Abstract
Callistemon citrinus is a medicinal herb of the Myrtaceae family. It is commonly
known for brush- like flowers, spiked flowers and attractive, papery bark shaggy,
dark-grey and long fibrous strands. It is distributed in moist conditions and thrives
on regular watering. These flowers and leaves are droopy and multi-trunked without
any thorns. Osteosarcoma, a bone cancer, typically affects long bones of arms and
legs, but can occur in any bone. The plant is traditionally used in the treatment
of skin infection (scabies, blotch, herpes and eczema) and cancer (carcinogenesis,
Colorectal Cancer, osterosarcoma) etc.
The study is aimed at unveiling the ethnobotanical description and phytochemical,
anti -oxidant, anti-inflammatory, anti- microbial activities and to investigate
the cytotoxic and anti-cancer potential of Bottlebrush bark extract on bone cancer
cell lines through an in vitro study of C. citrinus. The objective of the study
was to explore the antioxidant, antimicrobial and anticancer potential of Callistemon
citrinus (Red Bottlebrush) bark extracts in a bone cancer cell line.
