Comparative study
to evaluate the anti-diabetic and anti-bacterial potential of Tinospora cordifolia
and Catharanthus roseus plant extracts
Thakur Shriyanshu, Sharma Shivam and Gupta Rolika
Res. J. Biotech.; Vol. 20(10); 35-40;
doi: https://doi.org/10.25303/2010rjbt035040; (2025)
Abstract
Tinospora cordifolia (Giloy) and Catharanthus roseus (Sadabahar) possess an abundance
of bioactive substances and other advantageous attributes. Methanolic extracts of
the entire plant from both plants were examined in the in vitro investigation for
their anti-bacterial and anti-diabetic properties. The results of the anti-bacterial
activity demonstrated that the methanolic plants extract had anti-bacterial activity
against Staphylococcus aureus, Escherichia coli and Bacillus subtilis bacteria.
In comparison to T. cordifolia, C. roseus showed the maximum zone of inhibition.
Extracts from C. roseus exhibit a higher α-amylase inhibitory activity (55.43%)
in comparison to extracts from T. cordifolia (53.44%) thus proving higher anti-diabetic
potential. The methanolic extract of both plants contained phenols, flavonoids,
proteins, carbohydrates and sterols, based on the results of the qualitative analysis
of significant secondary metabolites. The current study has therefore concluded
that T. cordifolia and C. roseus, two medicinal plants, may aid in the discovery
of novel medications that may be used as treatments for bacterial and diabetes ailments
that are resistant to current medications.
