Antibiofilm effects
of tannins from Delonix elata Linn.
Rajeswari G., Doss A., Kumari Pushpa Rani T.P. and Praveen Pole R.P.
Res. J. Biotech.; Vol. 20(9); 277-282;
doi: https://doi.org/10.25303/209rjbt2770282; (2025)
Abstract
Biofilm is a complex microbial population that is resistant to antimicrobials. The
production of biofilms on biotic and abiotic surfaces causes high rates of morbidity
and mortality in hospitalized patients. In the present study, the antibacterial
and antibiofilm potential of crude tannins (ethanol and aqueous extracts) were employed
against microbial pathogens. The minimum inhibitory concentration (MIC) and minimum
bactericidal concentration (MBC) were determined ranging from 0.125 – 8 μg/ml.
The specific biofilm formation index (SBF) was evaluated before and after the addition
of plant extracts and tannins. Tannins caused a major reduction in biofilm formation
by S. aureus (69.02%). The crude extracts and tannins may be potential candidates
for the development of antibacterial drugs.