Green Synthesis
and Functionalization of Au Nanoparticles using Syzygium samarangense Leaf Extract
and its Biological Applications
Chaudhary Leela, Chaudhary Mansi, Patel Nidhi, Moga Himani and Makvana Chirag
Res. J. Biotech.; Vol. 20(9); 118-126;
doi: https://doi.org/10.25303/209rjbt1180126; (2025)
Abstract
Nanotechnology has revolutionized various industries with gold nanoparticles (AuNPs)
being particularly significant due to their biocompatibility and versatile applications.
Traditional synthesis methods for AuNPs often involve harsh chemicals, raising concerns
about environmental sustainability. Using leaf extract from Syzygium samarangense
as a reducing agent, this work investigates the green synthesis of AuNPs which provides
a more environmentally friendly technique. The leaf extract's abundant phytoconstituents,
such as phenolic acids and flavonoids, stabilize the nanoparticles in addition to
lowering the gold ions.
To further improve these AuNPs' stability and biocompatibility, we functionalized
them using polyvinyl pyrrolidone (PVP). The effective synthesis and functionalization
of the produced PVP-b-AuNPs were confirmed by characterization utilizing FTIR, HR-TEM,
XRD and UV-Vis spectroscopy. Biological evaluations revealed that PVP-b-AuNPs exhibit
superior antioxidant and antimicrobial activities compared to unfunctionalized b-AuNPs.
These findings highlight the potential of S. samarangense leaf extract in the sustainable
synthesis of functionalized AuNPs, providing a scalable, eco-friendly alternative
for applications in healthcare and other industries.
