Bacterial showdown:
Chronic Osteomyelitis Types vs their Microbial Foes
Jagan V., V. Vijaya Swetha and N. Padma Priya
Res. J. Biotech.; Vol. 21(2); 28-32;
doi: https://doi.org/10.25303/212rjbt028032; (2026)
Abstract
Osteomyelitis is a bone infection which occurs due to the extension from an infected
joint or by direct invasion because of trauma or instrumentation. Inoculation of
micro-organisms into the bone matrix may occur during fixation of the fracture,
implanting prosthesis or due to trauma. The study was conducted from during April
2021 to March 2022 study period, the patients diagnosed as chronic pyogenic osteomyelitis
by clinical and radiological examination were included in the study.
Etiology of osteomyelitis such as trauma (45%) and prosthetic implant in-situ (41%)
are the major causes. Tibia (42%) followed by femur (34%) are the most common bones
involved. Among the 100 cultures, total of 112 pathogens were isolated. Among 112
isolates, 77 (68.8%) were Staphylococcus aureus, 21 (18.8%) were Pseudomonas aeruginosa,
06 (5.4%) were Escherichia coli, 06 (5.4%) were Enterococcus faecalis and 02(1.6%)
were Proteus mirabilis. The most common pathogen encountered during the study in
cases of chronic pyogenic osteomyelitis was Staphylococcus aureus (68.8%). The antibiotic
susceptibility testing showed that 36(46.8%) isolates were MRSA and rest 41 (53.2%)
were MSSA. The 36 MRSA strains were tested for Vancomycin sensitivity by E-strip
test and all were sensitive for Vancomycin.
