Research Journal of Chemistry

and Environment


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Dihydropyrimidine thione derviatives: Preparation, In silico studies, In vitro Antioxidantal and Antibacterial activity

Divya Puskuri, Badithapuram Vinitha, Velidandi Amarnath and Siddoju Kavitha

Res. J. Chem. Environ.; Vol. 29(12); 113-117; doi: https://doi.org/10.25303/2912rjce1130117; (2025)

Abstract
Thioxo pyrimidine derivatives play a vital role in the preparation of antimicrobial, antitumor, antiulcer and anticonvulsant drugs. Herein, we discussed the synthesis, in silico studies, anti-microbial activity and anti-oxidant activity of A (1-6), A1 (1-6) compounds. Titled compounds are non-polar. Results of biological studies indicate that these precursors can be used as anti bacterial, antioxidant and anti cancer agents.