New symbiotic
antifungal strategies based on medicinal plants and metal complexes
Bharti Dipti, Kumar Ashish, Tiwari Brij Kishore, Akbar Ali and Singh Rahul
Res. J. Chem. Environ.; Vol. 29(6); 1-6;
doi: https://doi.org/10.25303/296rjce0106; (2025)
Abstract
The combination of previously manufactured metal complexes with extracts from medicinal
herbs such as Withania somnifera, Azadirachta indica, Ocimum sanctum and Tinospora
cordifolia L., renowned for their intrinsic antimicrobial activities, produced a
synergistic effect. Comparative investigation demonstrated that medicinal plant
extracts mixed with metal complexes had higher antimycotic action than individual
metal complexes or plant extracts alone.
Notably, cadmium ferrocyanide combined with Tinospora cordifolia extract and copper
ferrocyanide combined with Withania somnifera extract exhibited the highest antimycotic
activities against Phytopthora infestans, the causal agent of late blight in potatoes.
These findings show that synergistic interactions between metal complexes and medicinal
plant extracts improve antimicrobial activity, underlining their potential as long-term
disease management options.
