Effect of different
solvent extracts on total phenol content, flavonoid content and antioxidant properties
of Strobilanthes cordifolia (Vahl) J.R.I. Wood
Mohankumar Harshini, Soundararajan Deepa and Raju Prabakaran
Res. J. Chem. Environ.; Vol. 29(3); 13-19;
doi: https://doi.org/10.25303/293rjce013019; (2025)
Abstract
The antioxidant quality of plant-derived products is widely acknowledged to be influenced
by various extraction factors such as the method employed, temperature, duration
and choice of solvent system. The objective of the current study was to assess how
various solvents affect the extraction yields, phytochemical components and antioxidant
properties of S. cordifolia leaves. In this study, hexane, chloroform, ethanol and
aqueous were used as extraction solvents for S. cordifolia. Ethanol was found to
be the most effective solvent, resulting in the maximum extraction yield (24.46±1.03%)
and the highest amount of phenolic (84.5 ± 0.5 mg GAE/g) and flavonoids (50.59 ±
0.65 mg QE/g) in the crude extract. The antioxidant activities of S. cordifolia
were assessed using DPPH, ABTS and H2O2 assays. The ethanol extract showed substantial
efficacy in scavenging DPPH, ABTS and H2O2 with IC50 values of 65.3μg/mL, 68.1μg/mL
and 75.8μg/mL respectively.
Moreover, each solvent extract derived from S. cordifolia exhibited significant
antioxidant potential, albeit with variations attributed to differences in their
phytochemical composition. These findings highlight the potential of S. cordifolia
leaves as a natural antioxidant source, promising in alleviating oxidative stress
and holding significance for the nutraceutical and pharmaceutical industries. Future
investigations should prioritize isolating and identifying the active secondary
metabolites present in these extracts.
