Anti-Diabetic
Activity of Bougainvillea glabra mediated Silver Nanoparticles
Vidhya S., Leema Rose A., Janeeta Priya F., Jency H. and Prema M.
Res. J. Chem. Environ.; Vol. 29(5); 57-65;
doi: https://doi.org/10.25303/295rjce057065; (2025)
Abstract
The present study concentrates on the green synthesis of silver nanoparticles (AgNPs)
from methanol bark extract of Bougainvillea glabra. The phytocomponents’ presence
causes the metal ions to be reduced and the silver nanoparticles to become stabilized.
Green synthesis of silver nanoparticles was characterized by UV-Visible, DLS TEM
and X-ray diffraction analysis. TEM and XRD study showed that the particles are
crystalline in nature with face centred cubic geometry. EDX analysis shows the presence
of silver element. In the present study, Bougainvillea glabra mediated silver nanoparticles
were studied using an in vitro model for alpha amylase and alpha glucosidase inhibition.
Antioxidant activity was also examined by using free radical scavenging method while
compared to standard acarbose. The BG-AgNps exhibits considerable inhibitory effects
against 70.85% α-amylase and 78.04% α-glucosidase at a 100 μg/ml concentration respectively.
Therefore, BG-AgNps have enriched herbal antidiabetic and antioxidant compounds
and will have capacity for controlling diabetes mellitus.
