Graphite-Catalysed
Synthesis of phenolic Schiff’s Bases: Rapid, Efficient and Environmentally benign
Synthetic Approach
Naik Sneha, Tiwari Richa, Chauhan Manmohan Singh, Srivastava Sonia Chahar and Lamba
Narendra Pal
Res. J. Chem. Environ.; Vol. 29(5); 128-144;
doi: https://doi.org/10.25303/295rjce1280144; (2025)
Abstract
Herein we report a rapid and straightforward approach for the synthesis of phenolic
Schiff bases employing graphite, a versatile form of carbon, as an effective heterogeneous
catalyst. The synthesis involved the reaction of differently substituted aromatic
aldehydes with o-amino phenol in ethanol solvent under reflux conditions, utilizing
a catalytic amount of readily available graphite powder.
This environmentally benign procedure offers several notable advantages including
high product yields, the accessibility of the catalyst, simplified workup processes,
short reaction times and advantages of recycling. Exploring the use of graphite
as a catalyst in organic synthesis reveals its potential as an efficient and sustainable
alternative. The method's simplicity and efficiency make it a promising pathway
for the preparation of phenolic Schiff bases, showcasing the versatility and applicability
of graphite in catalytic processes.
