Research Journal of Chemistry

and Environment


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Bioactive properties and LC-MS analysis of water dropwort plant

Kumar Rajneesh and Singh Pooja

Res. J. Chem. Environ.; Vol. 29(9); 67-74; doi: https://doi.org/10.25303/299rjce067074; (2025)

Abstract
Oenanthe javanica commonly known as water celery or dropwort is a medicinal plant with a wide spectrum of biological properties. Present study was done to evaluate the antibacterial activity of Oenanthe javanica essential oil (OJEO) against Escherichia coli (ATCC 25922) and Bacillus cereus (ATCC 11778). It showed 13±0.57 mm and 12±0.57 mm zone of inhibition against B. cereus and E. coli. Scanning Electron Microscopy imaging was done to confirm the altered bacterial surface morphology on OJEO treatment. OJEO showed 65.09% radical scavenging activity as evaluated by DPPH assay. OJEO also exhibited cytotoxicity against HaCat cell lines by NRU assay.

Liquid chromatography- mass spectrometry (LC-MS) analysis revealed the presence of luteolin, xanthosine, acacetin, scoulerin and other biologically active compounds. In recent decades, antimicrobial resistance has become a worldwide threat. Plant based natural products and their basal formulations can be used as therapeutics, in food preservation and in pharma-based industries.