In vitro Antiurolithiatic
Activity of Methanolic Extract of Fruit Pulp of Two Varieties of Lansium domesticum
Correa (Meliaceae)
Sruthi Gopan M. and Sudha Bai R.
Res. J. Chem. Environ.; Vol. 30(1); 58-63;
doi: https://doi.org/10.25303/301rjce058063; (2026)
Abstract
Lansium domesticum Correa, native to Southeast Asian countries, is a tree bearing
exotic fruit that belongs to the family Meliaceae. The tropical fruit tree consists
of bunches of edible fruits borne on its branches. The aril of the fruits appeared
as a white translucent part and is the edible portion for consumption. Lansium domesticum
var. domesticum (LDD) and Lansium domesticum var. pubescens (LDP) are commonly known
as Duku and Langsat, respectively. This is a seasonal fruit that contains vitamins,
minerals and is used traditionally as medicine.
In addition to the aril of the fruits, their peel and seeds also have several medicinal
properties and are used as raw medicines. The peel is used as an insect repellent
and is visible as brownish in color. The present analysis clearly gives the vision
about the antiurolithiatic potential of the plant. The methanolic extract from the
fruit pulp of (mg/g) LDD (0.9997±1.1×10−4) and LDP (0.9994±0.00) has a higher potential
to dissolve the calcium oxalate crystals than the standard drug, Cystone and potassium
citrate. The methanolic fruit pulp extract of Lansium domesticum can be used as
a natural drug for treating various urogenital diseases, especially kidney stones.
