Research Journal of Biotechnology

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Vol. 20(11) November 2025

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1. Unlocking the potential of Vibrio natriegens for L-lysine production

Nghiem Thi Tuoi, Tran Huong Ly, Nguyen Tien Thanh, Le Thanh Ha and Le Quang Hoa

Page No: 1-9; doi: https://doi.org/10.25303/2011rjbt0109; Full Text

2. Isolation and phylogenetic characterisation of an antimicrobially active bacterial strain from the Telescopium telescopium

Yedla Suneetha, Upmaka Yamini and Gudivada Mani

Page No: 10-20; doi: https://doi.org/10.25303/2011rjbt010020; Full Text

3. Structural insight into PNAG binding and partial De-N-acetylation modification site of IcaB protein in Staphylococcus epidermidis

Ramachandira Prabu, Mohanty Amaresh Kumar, Raziya Shaik, Sarada R. and Veeramani T.

Page No: 21-29; doi: https://doi.org/10.25303/2011rjbt021029; Full Text

4. Unraveling the Structural Consequence of Pathogenic Single Nucleotide Polymorphisms in the Human Aldosterone Synthase: An in silico Approach

Dhamodharan Prabhu, Murugan Mukilan, Muthu Krishnan Dhivya Dharshini, Vairavanathan Jayavarshini and Gopalakrishnan Velliyur Kanniappan

Page No: 30-41; doi: https://doi.org/10.25303/2011rjbt030041; Full Text

5. Influence of cultural conditions on enhancing chitinase produced by Paenibacillus polymyxa M6 strain isolated from soil at Thanh Tra pomelo (Citrus grandis (L.) Osbeck) farm in Vietnam

Hoang Ha My A., Trai Vo Thi Ngoc, Dung Tran Quoc and Hung Nguyen Bao

Page No: 42-48; doi: https://doi.org/10.25303/2011rjbt042048; Full Text

6. Study on the effect of topical Nepafenac 0.1% w/v in preventing Macular edema after cataract surgery in patients with diabetes

Ramalingam Kothai, Kalaimamani Ezhilvendhan, Iyyappan Saranya, Sivamurugan Rajesh Kanna and Vijayan Roshini

Page No: 49-53; doi: https://doi.org/10.25303/2011rjbt049053; Full Text

7. The study of Non-Tuberculous Aerobic bacterial and fungal profile of Lower Respiratory tract infection in Tertiary Care Centre

Euphrasia Latha J., Sinduja S., Renuga S. and Arumai A.S.

Page No: 54-59; doi: https://doi.org/10.25303/2011rjbt054059; Full Text

8. Optimization of Indigenous Alkalophilic Bacteria of Sambhar Lake on B4 Medium

Rani Ujjwala and Gupta Varsha

Page No: 60-67; doi: https://doi.org/10.25303/2011rjbt060067; Full Text

9. Unveiling Machine Learning Algorithms for predicting Drug Activity against Lung Cancer Cell Lines

Kanagasabapathy Gokulakrishnan, Krishnamoorthy Hema Nandini Rajendran, Veerappapillai Shanthi, Pachaiappan Jayakrishnan and Karuppasamy Ramanathan

Page No: 68-75; doi: https://doi.org/10.25303/2011rjbt068075; Full Text

10. Genetic Pathway Analysis of Inattentive Disorder Symptoms: A GWAS Study Analysis

Dinesh P., Adiga Usha, Jayapriya T., Vasishta Sampara and Manikyam M.

Page No: 76-84; doi: https://doi.org/10.25303/2011rjbt076084; Full Text

11. Uncovering Novel Gene Signatures involved in chromosomes segregation in Triple-Negative Breast Cancer using Differential Transcriptome Analysis

Tiwari Prashant Kumar, Mishra Santosh Kumar, Singh Himanshu Narayan and Kumar Sanjay

Page No: 85-97; doi: https://doi.org/10.25303/2011rjbt085097; Full Text

12. Incidence of laccase and biosurfactant producing bacteria from mesophilic to extreme environments to harness potential contribution in dye degradation and antimicrobial activity

Peter Jyotsna K., Kumar Arun, Yadav Ashok K. and Mehta Praveen K.

Page No: 98-108; doi: https://doi.org/10.25303/2011rjbt0980108; Full Text

13. Impact of Hybrid Nanoparticles (Au, Cu/Blood-Mediated) Transport in Stenotic and Aneurysmal Curved Artery with Gyrotactic Microorganism: Hematocrit-Based Viscosity Framework

Sarowa Sumit, Kumar Surendra and Yadav Yashasvi

Page No: 109-119; doi: https://doi.org/10.25303/2011rjbt1090119; Full Text

14. Integrated Network Pharmacology and Molecular Docking to understand the Mechanisms of Methotrexate-induced Intestinal Toxicity

Charles Doveit Antony, Katturajan Ramkumar, Thirunavukarasu Muthu Kumar and Evan Prince Sabina

Page No: 120-127; doi: https://doi.org/10.25303/2011rjbt1200127; Full Text

15. Identification of response regulator genes of Xanthomonas oryzae pv. oryzae involved in the c-di-GMP signaling

Porwal Priyanshi and Pandey Alok

Page No: 128-131; doi: https://doi.org/10.25303/2011rjbt1280131; Full Text

16. Pharmacological effect of Cassia auriculata against Pediculosis humanus capitis infestations as a public health problem

Faleh A. AlFaleh

Page No: 132-141; doi: https://doi.org/10.25303/2011rjbt1320141; Full Text

17. In vitro Propagation and Variation of Antioxidant and Docking Properties of Bacopa monnieri (L.) Wettst. a Threatened Medicinal Plant

Govindarasu Sekar and Shanmugasundharam Murugesh

Page No: 142-149; doi: https://doi.org/10.25303/2011rjbt1420149; Full Text

18. Comparison of Serological and Hematological markers in Dengue: A Cross-sectional study

Balaji Vignesh Kanna, Sekar Jayapradha and Indernath Sunil

Page No: 150-153; doi: https://doi.org/10.25303/2011rjbt1500153; Full Text

19. Green-Synthesized Nano-Hydroxyapatite using Terminalia arjuna enhancing Osteogenesis in MG-63 Cells: A Promising Approach for Bone Regeneration

Suba Sri M. and Usha R.

Page No: 154-173; doi: https://doi.org/10.25303/2011rjbt1540173; Full Text

20. In vitro α-amylase and α-glucosidase Inhibition, Antioxidant and GC-MS Profiling of Ziziphus oenoplia

Khan Rahamat, Tummalagunta Ranganath, Kannan Kanmani, Sorimuthu Anbalagan and Muruganantham Sankareswaran

Page No: 174-185; doi: https://doi.org/10.25303/2011rjbt1740185; Full Text

21. Green synthesis of silver nanoparticles using P. guajava L. extract prepared by ultrasonic-assisted extraction, as reducing agent for wound dressing application: In vitro and in vivo evaluation

Quang Minh Tran, Thi Ngoc Tran Tran, Chi Nhan Ha Thuc and Ngoc Ha-Thu Le

Page No: 186-194; doi: https://doi.org/10.25303/2011rjbt1860194; Full Text

22. Efficacy of Metal Accumulation and Bioremediation Potential of Ascidians from the Thoothukudi Coast

Subashini N. and Tamilselvi M.

Page No: 195-204; doi: https://doi.org/10.25303/2011rjbt1950204; Full Text

23. A comprehensive study of tuna dry fish protein hydrolysates (DFPH) via papain-mediated hydrolysis and fermentation with Lactobacillus delbrueckii

Mariam Nooru K., Samson Lijoseraj C., Sarah Sundar Blessy and Premina S.

Page No: 205-213; doi: https://doi.org/10.25303/2011rjbt2050213; Full Text

24. Molecular Docking and Network-Based Analysis of Piper betle Linn Phytochemicals as Potential GABA_A Receptor Modulators for Neuroprotection

Mohan Gaanappriya and Kesavan Amala

Page No: 214-224; doi: https://doi.org/10.25303/2011rjbt2140224; Full Text

25. Protocadherin Alpha-1 (PCDHA1): A Key Regulator of Neural Connectivity and Synaptic Organization

Peddareddemma P., Adiga Usha S., Vasishta Sampara, Supriya P. and Augustine Alfred J.

Page No: 225-232; doi: https://doi.org/10.25303/2011rjbt2250232; Full Text

26. Degradation of chicken feather using keratinase enzyme produced by Bacillus thuringiensis SJAMB and biofertilizing prospective for agriculture practices

Janani S., Akilandeswari P. and Pradeep B.V.

Page No: 233-240; doi: https://doi.org/10.25303/2011rjbt2330240; Full Text

27. Extraction, Phytochemical Analysis, GC-MS Characterization and Larvicidal Activities of Leaf Extracts of Leucas aspera and Xanthium strumarium on Spodoptera Larva

Nagarathinam T., Raja Rajeswari A. and Umamaheswari S.

Page No: 241-248; doi: https://doi.org/10.25303/2011rjbt2410248; Full Text

28. Mammogram image modalities utilizing novelty of fuzzy segmentation for image enhancement of breast cancer identification

Jeevitha V. and Laurence Aroquiaraj I.

Page No: 249-257; doi: https://doi.org/10.25303/2011rjbt2490257; Full Text

29. Evaluation of phytochemicals, in vitro antioxidant and antidiabetic activities of Aquilaria malaccensis Lam.

Kalita Partha Pratim, Saikia Surovi and Kashyap Bhargav

Page No: 258-263; doi: https://doi.org/10.25303/2011rjbt2580263; Full Text

30. Screening and Evaluation of Antioxidant and Cytotoxic Potential of Herbal Mixture with Annona muricata and Guilandina bonduc against Cancer lines (A 549, SiHa, HeLa) -A Systematic Study

Koshy Feba Sara, Karpakavalli M., Chandrasekaran Rajkuberan, Ranjithkumar D. and Sangilimuthu Alagar Yadav

Page No: 264-271; doi: https://doi.org/10.25303/2011rjbt2640271; Full Text

31. Evaluation of Thyroid Dysfunction and Autoimmunity in Gestational Diabetes Mellitus

Sudhakar S., Vijayasamundeeswari C.K., Ramakrishnan T., Sinju R. and Sudha R.

Page No: 272-276; doi: https://doi.org/10.25303/2011rjbt2720276; Full Text

32. Differential Gene Expression Analysis of Latent and Active Tuberculosis used for Machine Learning Guided Therapeutic Peptide Design

Baothman Othman A.

Page No: 277-292; doi: https://doi.org/10.25303/2011rjbt2770292; Full Text

33. Pharmacognostic standardization and HPTLC fingerprint profile of Careya arborea Roxb. stem bark

Gupta Priyanka, Patil Darshana and Patil Avinash

Page No: 293-299; doi: https://doi.org/10.25303/2011rjbt2930299; Full Text

34. In vitro Antimicrobial activity and Qualitative Enzymatic assays of Cladosporium pseudocladosporidiales, AVNK4, an endophytic fungus isolated from seeds of Nigella sativa

Shaik Mahekal Kousar, Krishnaveni Vunnam and Amrutha Valli Audipudi

Page No: 300-309; doi: https://doi.org/10.25303/2011rjbt3000309; Full Text

35. Computational genome analysis of virulent genes and genetic code detection of Omicron Sars-Cov-2 variant and differential gene expression

Menon Sudheer

Page No: 310-324; doi: https://doi.org/10.25303/2011rjbt3100324; Full Text

36. Development and characteristics of spray-dried hydrolysates from limited hydrolysis of shark meat

Diniz Fábio Mendonça

Page No: 325-330; doi: https://doi.org/10.25303/2011rjbt3250330; Full Text

37. Hepatitis B Virus: A Comprehensive Overview of Virology, Transmission and Clinical Management

Durgadevi J. and Manisha Koyimadatha

Page No: 331-341; doi: https://doi.org/10.25303/2011rjbt3310341; Full Text

38. Recent advancements in valorisation of Pongamia pinnata, a versatile legume tree for bioenergy and biofuel applications

Payal, Singh Akhil, Kumar Shivam and Rachapudi Venkata Sreeharsha

Page No: 342-357; doi: https://doi.org/10.25303/2011rjbt3420357; Full Text

39. Unveiling Future Advancements in Azo Dye Degradation and Enhanced Bioelectricity Production using Microbial Fuel Cells

Chugh Ananya, Rai Riya and Sharma J.G.

Page No: 358-367; doi: https://doi.org/10.25303/2011rjbt3580367; Full Text

40. Methodologies for determination of antimicrobial resistance in commensal and pathogens of aquaculture

Vaiyapuri Murugadas, Mothadaka Mukteswar Prasad, Sivam Visnuvinayagam, Sumathi Ezhil Nilavan, Badireddy Madhusudana Rao and Nagarajarao Ravishankar Chandragiri

Page No: 368-389; doi: https://doi.org/10.25303/2011rjbt3680389; Full Text

41. Review on Amikacin resistance in Uropathogens

Senthil Kumar B., Rajan Reena and Karthikeyan G.

Page No: 390-394; doi: https://doi.org/10.25303/2011rjbt3900394; Full Text

42. Bioprospecting Actinomycetes from the Rhizosphere of Piper nigrum: Potential and Challenges

Balaji Muralikrishnan, Senthil Kumar J. and Ashwini Malla

Page No: 395-401; doi: https://doi.org/10.25303/2011rjbt3950401; Full Text

43. Assessing the Current Status of Artificial Intelligence Applications for Predicting Microsatellite Instability in Colon Cancer

Alsughayyir Jawaher

Page No: 402-416; doi: https://doi.org/10.25303/2011rjbt4020416; Full Text